Red Orange: Experimental Models and Epidemiological Evidence of Its Benefits on Human Health
Identifieur interne : 000D40 ( Main/Exploration ); précédent : 000D39; suivant : 000D41Red Orange: Experimental Models and Epidemiological Evidence of Its Benefits on Human Health
Auteurs : Giuseppe Grosso [Italie] ; Fabio Galvano [Italie] ; Antonio Mistretta [Italie] ; Stefano Marventano [Italie] ; Francesca Nolfo [Italie] ; Giorgio Calabrese [Italie] ; Silvio Buscemi [Italie] ; Filippo Drago [Italie] ; Umberto Veronesi [Italie] ; Alessandro Scuderi [Italie]Source :
- Oxidative Medicine and Cellular Longevity [ 1942-0900 ] ; 2013.
English descriptors
- KwdEn :
- MESH :
- chemical , pharmacology : Anti-Inflammatory Agents, Phytochemicals.
- chemistry : Citrus sinensis.
- Beverages, Health, Humans, Models, Biological.
Abstract
In recent years, there has been increasing public interest in plant antioxidants, thanks to the potential anticarcinogenic and cardioprotective actions mediated by their biochemical properties. The red (or blood) orange (
Url:
DOI: 10.1155/2013/157240
PubMed: 23738032
PubMed Central: 3659473
Affiliations:
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Sofia No. 85-95123, Catania</wicri:regionArea><wicri:noRegion>Catania</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I2">Section of Biochemistry, Department of Drug Sciences, University of Catania, Catania, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Biochemistry, Department of Drug Sciences, University of Catania, Catania</wicri:regionArea><wicri:noRegion>Catania</wicri:noRegion></affiliation></author><author><name sortKey="Galvano, Fabio" sort="Galvano, Fabio" uniqKey="Galvano F" first="Fabio" last="Galvano">Fabio Galvano</name><affiliation wicri:level="1"><nlm:aff id="I2">Section of Biochemistry, Department of Drug Sciences, University of Catania, Catania, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Biochemistry, Department of Drug Sciences, University of Catania, Catania</wicri:regionArea><wicri:noRegion>Catania</wicri:noRegion></affiliation></author><author><name sortKey="Mistretta, Antonio" sort="Mistretta, Antonio" uniqKey="Mistretta A" first="Antonio" last="Mistretta">Antonio Mistretta</name><affiliation wicri:level="1"><nlm:aff id="I1">Section of Hygiene and Public Health, Department of G.F. Ingrassia, University of Catania, Via S. Sofia No. 85-95123, Catania, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Hygiene and Public Health, Department of G.F. Ingrassia, University of Catania, Via S. Sofia No. 85-95123, Catania</wicri:regionArea><wicri:noRegion>Catania</wicri:noRegion></affiliation></author><author><name sortKey="Marventano, Stefano" sort="Marventano, Stefano" uniqKey="Marventano S" first="Stefano" last="Marventano">Stefano Marventano</name><affiliation wicri:level="1"><nlm:aff id="I1">Section of Hygiene and Public Health, Department of G.F. Ingrassia, University of Catania, Via S. Sofia No. 85-95123, Catania, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Hygiene and Public Health, Department of G.F. Ingrassia, University of Catania, Via S. Sofia No. 85-95123, Catania</wicri:regionArea><wicri:noRegion>Catania</wicri:noRegion></affiliation></author><author><name sortKey="Nolfo, Francesca" sort="Nolfo, Francesca" uniqKey="Nolfo F" first="Francesca" last="Nolfo">Francesca Nolfo</name><affiliation wicri:level="1"><nlm:aff id="I1">Section of Hygiene and Public Health, Department of G.F. Ingrassia, University of Catania, Via S. Sofia No. 85-95123, Catania, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Hygiene and Public Health, Department of G.F. Ingrassia, University of Catania, Via S. Sofia No. 85-95123, Catania</wicri:regionArea><wicri:noRegion>Catania</wicri:noRegion></affiliation></author><author><name sortKey="Calabrese, Giorgio" sort="Calabrese, Giorgio" uniqKey="Calabrese G" first="Giorgio" last="Calabrese">Giorgio Calabrese</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of Biology, Piemonte Orientale University, Alessandria, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Biology, Piemonte Orientale University, Alessandria</wicri:regionArea><wicri:noRegion>Alessandria</wicri:noRegion></affiliation></author><author><name sortKey="Buscemi, Silvio" sort="Buscemi, Silvio" uniqKey="Buscemi S" first="Silvio" last="Buscemi">Silvio Buscemi</name><affiliation wicri:level="1"><nlm:aff id="I4">Department of Internal Medicine, University of Palermo, Palermo, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Internal Medicine, University of Palermo, Palermo</wicri:regionArea><wicri:noRegion>Palermo</wicri:noRegion></affiliation></author><author><name sortKey="Drago, Filippo" sort="Drago, Filippo" uniqKey="Drago F" first="Filippo" last="Drago">Filippo Drago</name><affiliation wicri:level="1"><nlm:aff id="I5">Section of Pharmacology and Biochemistry, Department of Clinical and Molecular Biomedicine, University of Catania, Catania, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Pharmacology and Biochemistry, Department of Clinical and Molecular Biomedicine, University of Catania, Catania</wicri:regionArea><wicri:noRegion>Catania</wicri:noRegion></affiliation></author><author><name sortKey="Veronesi, Umberto" sort="Veronesi, Umberto" uniqKey="Veronesi U" first="Umberto" last="Veronesi">Umberto Veronesi</name><affiliation wicri:level="3"><nlm:aff id="I6">Department of Experimental Medicine, University of Rome “Sapienza”, Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Experimental Medicine, University of Rome “Sapienza”, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Scuderi, Alessandro" sort="Scuderi, Alessandro" uniqKey="Scuderi A" first="Alessandro" last="Scuderi">Alessandro Scuderi</name><affiliation wicri:level="1"><nlm:aff id="I7">Department of Agri-Food and Environmental Systems and Management (DIGESA), University of Catania, Catania, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Agri-Food and Environmental Systems and Management (DIGESA), University of Catania, Catania</wicri:regionArea><wicri:noRegion>Catania</wicri:noRegion></affiliation></author></analytic><series><title level="j">Oxidative Medicine and Cellular Longevity</title><idno type="ISSN">1942-0900</idno><idno type="eISSN">1942-0994</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anti-Inflammatory Agents (pharmacology)</term><term>Beverages</term><term>Citrus sinensis (chemistry)</term><term>Health</term><term>Humans</term><term>Models, Biological</term><term>Phytochemicals (pharmacology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Anti-Inflammatory Agents</term><term>Phytochemicals</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Citrus sinensis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Beverages</term><term>Health</term><term>Humans</term><term>Models, Biological</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>In recent years, there has been increasing public interest in plant antioxidants, thanks to the potential anticarcinogenic and cardioprotective actions mediated by their biochemical properties. The red (or blood) orange (<italic>Citrus sinensis</italic> (L.) Osbeck) is a pigmented sweet orange variety typical of eastern Sicily (southern Italy), California, and Spain. In this paper, we discuss the main health-related properties of the red orange that include anticancer, anti-inflammatory, and cardiovascular protection activities. Moreover, the effects on health of its main constituents (namely, flavonoids, carotenoids, ascorbic acid, hydroxycinnamic acids, and anthocyanins) are described. The red orange juice demonstrates an important antioxidant activity by modulating many antioxidant enzyme systems that efficiently counteract the oxidative damage which may play an important role in the etiology of numerous diseases, such as atherosclerosis, diabetes, and cancer. The beneficial effects of this fruit may be mediated by the synergic effects of its compounds. Thus, the supply of natural antioxidant compounds through a balanced diet rich in red oranges might provide protection against oxidative damage under differing conditions and could be more effective than, the supplementation of an individual antioxidant.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Galvano, F" uniqKey="Galvano F">F Galvano</name></author><author><name sortKey="La Fauci, L" uniqKey="La Fauci L">L La Fauci</name></author><author><name sortKey="Lazzarino, G" uniqKey="Lazzarino G">G Lazzarino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Amorini, Am" uniqKey="Amorini A">AM Amorini</name></author><author><name sortKey="Fazzina, G" uniqKey="Fazzina G">G Fazzina</name></author><author><name sortKey="Lazzarino, G" uniqKey="Lazzarino G">G Lazzarino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Galvano, F" uniqKey="Galvano F">F 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sortKey="Calabrese, Giorgio" sort="Calabrese, Giorgio" uniqKey="Calabrese G" first="Giorgio" last="Calabrese">Giorgio Calabrese</name><name sortKey="Drago, Filippo" sort="Drago, Filippo" uniqKey="Drago F" first="Filippo" last="Drago">Filippo Drago</name><name sortKey="Galvano, Fabio" sort="Galvano, Fabio" uniqKey="Galvano F" first="Fabio" last="Galvano">Fabio Galvano</name><name sortKey="Grosso, Giuseppe" sort="Grosso, Giuseppe" uniqKey="Grosso G" first="Giuseppe" last="Grosso">Giuseppe Grosso</name><name sortKey="Marventano, Stefano" sort="Marventano, Stefano" uniqKey="Marventano S" first="Stefano" last="Marventano">Stefano Marventano</name><name sortKey="Mistretta, Antonio" sort="Mistretta, Antonio" uniqKey="Mistretta A" first="Antonio" last="Mistretta">Antonio Mistretta</name><name sortKey="Nolfo, Francesca" sort="Nolfo, Francesca" uniqKey="Nolfo F" first="Francesca" last="Nolfo">Francesca Nolfo</name><name sortKey="Scuderi, Alessandro" sort="Scuderi, Alessandro" uniqKey="Scuderi A" first="Alessandro" last="Scuderi">Alessandro Scuderi</name><name sortKey="Veronesi, Umberto" sort="Veronesi, Umberto" uniqKey="Veronesi U" first="Umberto" last="Veronesi">Umberto Veronesi</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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